Abstract
BACKGROUND: Vacuum assisted closure therapy (VAC) is a noninvasive, cost-effective alternative to surgical wound management. Indigenous negative pressure wound therapy (NPWT) systems offer comparable clinical outcomes without financial constraints. MATERIALS AND METHODS: This prospective comparative study was conducted over 1 year at the Orthopedics department of RIMS, Ranchi. Eligibility criteria included patients with Gustilo-Anderson class 2, 3A, or 3B wounds, with exclusion criteria such as vascular injury or wound <10mm. Sample size was calculated to be 86 participants (43 per group). Data collection involved semi-quantitative wound assessments and wound surface area measurements, and statistical analysis was performed using SPSS software. Student t -test and Chi-square test were used to test statistical significance. RESULTS: The study revealed that the conventional negative pressure wound therapy led to faster wound healing, with a mean time of 31.1 days compared to 34.7 days in the indigenous therapy group. Assessment of wound bed score parameters showed similar results between the groups initially, with slight variations noted in certain aspects like severity of exposed bone/tendon during the second VAC applications. CONCLUSION: The study found that indigenous VAC therapy reduced wound healing time significantly. Both therapies had similar wound management outcomes, with minor differences in wound bed score parameters. However, conventional therapy displayed better wound healing progress. Complications were slightly lower but comparable in the indigenous group, suggesting indigenous VAC therapy as a cost-effective and safe alternative to conventional VAC therapy.