Variability of anti-staphylococcal antibodies in healthy volunteers and pre-cardiac surgery patients

健康志愿者和心脏手术前患者抗葡萄球菌抗体的变化

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作者:Sarka Moravcova, Bonnie Kyle, Hilary Shanahan, Savvas Giannaris, Andrew Smith, Colin Hamilton-Davies

Background

Pre-operative antibody levels have been shown to be inversely related to development of post-operative complications. Staphylococcal infection is a major source of morbidity following surgery.

Conclusions

The relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation.

Methods

We examined the variability of anti-staphylococcal antibody levels across a group of healthy volunteers and compared this with patients scheduled to undergo cardiac surgery.

Results

Pre-operative cardiac surgical patients exhibited significantly higher levels of staphylococcal antibodies compared with healthy volunteers. Conclusions: The relationship between pre-surgery staphylococcal antibody levels and outcome warrants further investigation.

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