Electrocatalysis by subcellular liver fractions bound to carbon nanostructures for stereoselective green drug metabolite synthesis

利用与碳纳米结构结合的亚细胞肝脏组分进行电催化,实现立体选择性绿色药物代谢物的合成

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Abstract

A novel, reusable, cofactor-free, and mediator-free human liver microsomal bioreactor constructed on carbon nanostructure electrodes for stereoselective green syntheses of drug metabolites and specialty chemicals is reported here for the first time. Drug metabolites are useful for examining pharmaceutical and pharmacological properties of new drugs under development.

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