A mouse monoclonal antibody against the γ2 subunit of GABAA receptors

针对GABAA受体γ2亚基的小鼠单克隆抗体

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Abstract

A mouse monoclonal antibody directed against the N terminal extracellular epitope of rat γ amino butyric acid (GABA) type-A (GABA(A)R) receptor γ2 subunit was generated. This antibody identified a protein of approximately 42 kDa in Western blot assays using rat and mouse hippocampal proteins. The antibody also detected the expression of γ2 subunit by immunohistochemistry and could immunoprecipitate the γ2 subunit.

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