Abstract
RATIONALE: Urethral stricture is the scarring and healing of the urethral epithelium or the corpus spongiosum layer just beneath it, following damage to the urethra for any reason. The curative and the gold-standard treatment is urethroplasty. The management of posterior urethral strictures is 1 of the most difficult problems for urologists and requires special attention and reconstructive experience. PATIENT CONCERNS: A 79-year-old male who developed osteomyelitis following posterior urethroplasty. DIAGNOSES: Osteomyelitis was diagnosed after magnetic resonance imaging and bone biopsy. Histopathological examination confirmed osteomyelitis, and tissue cultures grew Escherichia coli and Klebsiella species. INTERVENTIONS: The patient was initiated on intravenous meropenem therapy. Based on recommendations from clinical microbiology and infectious diseases specialists, a prolonged 6-week antibiotic regimen was administered. OUTCOMES: After parenteral antibiotic treatment, the patient's clinical and laboratory parameters returned to normal. LESSONS: To the best of our knowledge, this complication has not been previously described, making our case the first reported and, therefore, unique.