Upadacitinib for the Treatment of Cutaneous Crohn's Disease Presenting as Lymphangioma Circumscriptum

乌帕替尼用于治疗以局限性淋巴管瘤为表现的皮肤克罗恩病

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Abstract

Metastatic Crohn's disease refers to cutaneous Crohn's disease noncontiguous with the gastrointestinal tract. Vulvar lymphangioma circumscriptum is a rare manifestation of metastatic Crohn's disease, presenting as pink papillomatous or vesicular papules and plaques. Treatment options are limited and often invasive, and clearance is difficult to achieve. We report a novel case of vulvar lymphangioma circumscriptum secondary to Crohn's disease successfully managed with oral and topical Janus kinase inhibitors in combination with procedural therapies.

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