Abstract
Growth-hormone deficiency (GHD) is a common growth-related disease in children, and the main reason is the lack of growth hormone. In the oralfacial region, GHD often manifests as severe mandibular retraction, which increases the difficulty of clinical treatment. This article reports a case of severe mandibular retraction with GHD subjected to functional orthopedic treatment combined with differential-force technique, which yielded satisfactory results. This study can serve as a reference for clinical treatments of similar cases.