Novel genetic defects in primary ciliary dyskinesia affecting function of dynein arms and central pair apparatus

原发性纤毛运动障碍中影响动力蛋白臂和中央对装置功能的新型基因缺陷

阅读:2

Abstract

OBJECTIVE: To evaluate the functional outcome and extensor apparatus of operative management of intra-articular fractures of distal humerus using modification of the Triceps Tongue Flap approach. METHODS: This prospective study was conducted between June, 2012 to April,2014 in NIMS Medical College and Hospital, Jaipur, Rajasthan(India). We included 23 patients with intraarticular fractures of distal humerus that were managed surgically. Modification of Triceps Tongue Flap approach with Triceps flap in inverted 'V' shape was used. Follow-up was done using standard radiograph anteroposterior/lateral (AP/Lat) at immediate postoperative day, 1,3, 6 and 12 month intervals. Functional outcome was assessed using range of motion at elbow joint, Disability of Arm, Shoulder and Hand (DASH)Score and Objective Muscle Strength Testing (MRC Grade) of triceps muscle at 1,2, 3,6 and 12 month follow-up. RESULTS: Overall we included 23 patients of whom 16 (69.5%) were men and 7 (30.5%) were women with mean age of 34.6+4.8years. Mean duration of the follow-up was 12.9+1.1 months. Mean DASH Score at final follow up was 7.7+1.1(indicating mild residal impairment). Mean muscle strength at final follow-up was 4.7 ± 0.4 (Range 3 to 5). Mean flexion deformity at elbow was 9.2 ±0.9 (Range 5 to 45) degrees and mean arc of flexion extension as 119 ± 3.4(Range 65to 140) degrees. CONCLUSION: This approach provides an excellent exposure as well as a good functional outcome as measured by DASH score and full range of motion at the elbow joint with return of almost complete power of the extensor apparatus in patients with intra-articular fractures of distal humerus.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。