White light-induced cell apoptosis by a conjugated polyelectrolyte through singlet oxygen generation

白光通过共轭聚电解质产生单线态氧诱导细胞凋亡

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Abstract

A cationic conjugated polyelectrolyte (CPE) PPET3 with a poly(p-phenylene ethynylene terthiophene) backbone and quaternary ammonium side chains was designed and synthesized. It serves as an efficient photosensitizer for photodynamic therapy under white light irradiation and induces cell death through the mitochondrial apoptosis pathway.

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