Abstract
Corbicula clams are of important economic values. Corbicula clams have diverse reproductive characteristics, inhabiting both freshwater and estuary. Here, we constructed a chromosome-level genome of the estuarine C. fluminalis from China by combining HiFi sequencing and Hi-C technology. The assembled genome is 1,140.30 Mb with a scaffold N50 length of 58.80 Mb, and is anchored onto 19 pseudo-chromosomes. A total of 25,363 protein-coding genes were identified and 94.03% of the identified genes were annotated. Approximately 63.50% of the genome is consisted of repetitive elements. The genome synteny between C. fluminalis and Mercenaria mercenaria is highly conserved. The chromosome genome assembly of C. fluminalis is a valuable resource for active ingredient research, phylogenomic studies and comparative genomics of the Corbicula clams and related species.