Abstract
Hypersensitivity pneumonia is an immune-mediated inflammation of the lung parenchyma that occurs in previously susceptible individuals, after inhalation of antigens, usually organic. In recent years, various chemical agents have been described as inducers of hypersensitivity pneumonia, including exposure to high concentrations of pesticides. The objective of the present case report was to describe a possible association of hypersensitivity pneumonia with pesticide chronic inhalation and to draw attention to the importance of early diagnosis. The patient was 72-year-old man who worked for over 30 years as a health agent fumigating pesticides in rural and urban areas. He had progressive dyspnea and cough for the past 3 years. Chest tomography demonstrated parenchymal bands, honeycombing, and diffuse air trapping. Spirometry showed a severe restrictive pattern. Surgical lung biopsy was indicated, which confirmed the diagnosis of hypersensitivity pneumonia. Due to the wide use of pesticides in Brazil, the knowledge of their association with hypersensitivity pneumonia is of great importance in warning the teams involved in health care and surveillance of these workers, providing earlier diagnoses, with better prognosis. On the contrary, late diagnoses, such as that of the case reported, have important health impacts. As a priority, preventive measures must be taken to protect exposed individuals.