Abstract
BACKGROUND: Stroke survivors, particularly those of working age, are at an increased risk of recurrent stroke within one-five years of the initial event, largely due to suboptimal management of risk factors. This study aimed to identify lifestyle and occupational factors associated with recurrent stroke in this demographic population. METHODS: This case-control study included 100 patients with recurrent ischemic stroke and 200 ischemic stroke survivors without recurrence, who were recruited from the hospital database. Multivariate logistic regression was used to identify significant factors associated with recurrence, which were presented as adjusted odds ratios (aORs) with 95% confidence intervals (CIs). RESULTS: The mean age was 45.4 years (SD = 15.1) among cases and 50.6 years (SD = 6.5) among controls. The male-to-female ratios were 1.17:1 and 1.94:1 in the case and control groups, respectively. Significant factors associated with recurrent stroke included female sex (aOR: 1.83; 95% CI [1.10-3.29]), high fasting blood sugar (aOR: 3.70; 95% CI [1.66-8.27]), current alcohol consumption (aOR: 3.63; 95% CI [2.01-6.54]), sedentary lifestyle (aOR: 2.77; 95% CI [1.50-5.13]), and lack of workplace support for health (aOR: 2.02; 95% CI [1.13-3.63]). The associations between these factors and stroke recurrence varied according to the age group. CONCLUSIONS: This study highlights the critical role of modifiable lifestyle and occupational factors in stroke recurrence among working-age adults. Tailored age-specific prevention strategies-emphasizing physical activity, reduced alcohol use, and improved workplace health environments-may reduce the risk of recurrence and enhance health outcomes in this population.