Inhibited Expression of NLRP12 Promotes the Development of Triple-Negative Breast Cancer by Activating the NF-κB Pathway

抑制NLRP12表达通过激活NF-κB通路促进三阴性乳腺癌的发展

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作者:Wenbin Kuang, Qingdan Gu, Ying Zhou, Xiaoqin Xiao, Dabao He, Qiuchan Deng

Procedures

colony formation assay for proliferation, Transwell for migration and invasion, and Western blot for NF-κB and MAPK pathway-associated proteins. Finally, a xenograft mouse model was applied; the tumor volume and weight were determined, and NLRP12, p-IκBb-α, and p-IκBb-α expressions were evaluated using qPCR and Western blot.

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