Good things come in threes: Distinct C. elegans basement membranes utilize novel collagen IV trimers

好事成三:秀丽隐杆线虫独特的基底膜利用新型IV型胶原蛋白三聚体

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Abstract

The highly conserved basement membrane protein collagen IV is stereotypically composed of two α1 subunits and one α2 subunit. In this issue, Srinivasan et al. (https://doi.org/10.1083/jcb.202412118) show that specific C. elegans basement membranes include collagen IV trimers with other compositions, suggesting a new diversity.

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