Abstract
BACKGROUND: Interventions aimed to mitigate drug-related harm include drug checking, which invloves a chemical analysis of a drug sample alongside personalized harm reduction advise. The Drug Information and Monitoring System (DIMS) represents a network of Drug Checking Services (DCS) in the Netherlands, which people who use drugs (PWUD) may visit before consumption, though not consistently. This paper describes the characteristics and experienced effects of PWUD who have their drugs tested after use, in relation to the analysis results of the submitted drug sample and the setting of use. METHODS: Data was collected between 2018 until 2022 encompassing a range of characteristics provided by the visitors. Statistical analyses were performed to find associations between the type of effects the visitor experienced and the (mis)match with the expected content of the drug sample or setting in which the sample was used. RESULTS: 14% (N = 9472) of all samples submitted to DIMS (N = 66150) were used prior to attending a DCS. The majority of samples were sold as ecstasy (41%, N = 3460) and cocaine (17%, N = 1407). Most visitors were male (75%, N = 6359), purchased their drugs offline (96%, N = 8081), and reported having used the sample at a party/festival (43%, N = 3614), while 27% (N = 2320) used it in a home setting. Half of the visitors (49%, N = 4109) declared not having used the sample in combination with other psychoactive substances. Positive mental effects were less likely to be experienced when the detected drug content did not match the expected content, while negative mental effects were more likely. Moreover, visitors consuming their sample at a party/festival were more likely to experience positive mental and physical effects and less likely to experience negative mental and physical effects compared to people consuming their sample at home. CONCLUSIONS: By identifying the characteristics of PWUD who have their drugs tested after use and by demonstrating that not only a (mis)match with the expected drug content, but also the setting in which the substance was used was associated with the drug experience, improved strategies can be developed to encourage individuals to visit a DCS before consumption, thereby reducing drug-related harm.