Modulating the tumor microenvironment via oncolytic virus and PI3K inhibition synergistically restores immune checkpoint therapy response in PTEN-deficient glioblastoma

通过溶瘤病毒和PI3K抑制剂调节肿瘤微环境可协同恢复PTEN缺陷型胶质母细胞瘤的免疫检查点治疗反应。