Abstract
BACKGROUND: Fenestrated/Branched Thoracic Endovascular Aortic Repair (F/B-TEVAR) has emerged as a cornerstone treatment for various acute and subacute complex aortic arch diseases, but the high complication rate of F/B-TEVAR surgery continues to plague many patients. METHODS: A retrospective analysis was conducted on 246 patients with aortic arch lesions who underwent F/B-TEVAR across 4 hospitals from February 2018 to December 2024. Case information and follow-up outcomes were analyzed using multivariate correlation calculation and multivariate logistic regression to summarize the risk factors associated with postoperative complications. RESULTS: Postoperative complications were observed in 53 cases (21.5%). Statistically significant risk factors (all P < 0.05) included history of previous cerebral infarction, history of smoking, lesions involving branch arteries, and the aortic wall pathology (aortic atherosclerotic plaque, minute intermural hematomas, mural thrombus). CONCLUSIONS: This study identifies key independent risk factors for complications post F/B-TEVAR, emphasizing the potential benefit of 3D printing-assisted technology in reducing these risks. Further research is needed to validate these findings, which can help clinicians identify high-risk patients and implement appropriate interventions.