Abstract
Gastroesophageal reflux disease is a prevalent condition worldwide with a significant impact on patients' quality of life and a growing burden on healthcare systems. In Argentina, the prevalence of typical weekly symptoms is estimated at 23%, which is similar to rates reported in other Latin American regions. Although most patients with esophagitis respond adequately to proton pump inhibitors, up to 30 - 40% of cases may show a partial or inadequate response, particularly among those with non-erosive disease. In such cases, surgery is a valid and effective alternative. The aim of this review is to provide an up-to-date, evidence-based analysis of preoperative functional evaluation, surgical techniques, patient selection, and the relationship between gastroesophageal reflux disease and special conditions such as obesity or rheumatological diseases.