[Therapeutic Developments in Eosinophilic Esophagitis]

嗜酸性食管炎的治疗进展

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Abstract

Eosinophilic esophagitis (EoE) is a chronic immunoallergic disorder caused, in most cases, by a non-IgE mediated food allergy. Its current prevalence exceeds 1 case per 1,000 inhabitants in Spain and Europe, while it is emerging in South America. This review attempts to update the therapeutic novelties that have appeared in the last 5 years for either induction or maintenance in this pathology, including new anti-acid drugs (potassium competitive acid blockers), simplified optimization of dietary schemes, novel swallowed topical corticosteroids specifically developed for esophageal delivery, as well as the incorporation of biologic agents into the therapeutic algorithm of the disease. Endoscopic dilation continues to be a safe and effective complement for symptomatic improvement, in combination with anti-inflammatory treatments for the disease.

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