Hepatitis C: evaluation of outcomes and georeferencing of cases in Santa Cruz do Sul, Brazil, between 2002 and 2015. A cross-sectional study

丙型肝炎:2002 年至 2015 年巴西南圣克鲁斯省病例结果评估和地理参考。横断面研究

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作者:Lia Goncalves Possuelo, Daiane Perin, Patricia Faber Breunig, Daniel Felipe Schroeder, Manuela Filter Allgayer, Camilo Darsie, Marcelo Carneiro, Vanda Hermes, Jane Dagmar Pollo Renner

Background

Hepatitis C virus infection is one of the main causes of chronic liver disease, with high death rates. The

Conclusion

The population consisted of adults aged 41 years and over, mostly with chronic hepatitis C. The most common transmission routes were illicit drug injection and blood transfusions. There were high rates of HIV coinfection and abandonment of disease monitoring and predominance of cases in neighborhoods with low socioeconomic status.

Methods

Secondary data including sociodemographic and clinical variables and type of outcome (death, follow-up, abandonment or clinical cure) were gathered. The spatial distribution analysis on hepatitis C virus cases according to outcome was based on information regarding residential address.

Results

58.5% of the patients were 41 years of age and over, 67% were males and 92.5% had the chronic form of the disease. The most frequent transmission route was illicit drug injection (29%); 15.1% of the patients presented coinfection with the human immunodeficiency virus (HIV). Regarding outcomes, 31% achieved clinical cure, 10% died and 20% abandoned follow-up. The cases studied were mainly located in regions of the city characterized by lower socioeconomic status, with high frequency of places used for drug trafficking.

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