Abstract
OBJECTIVES: The aim of this review was to describe malnutrition and poor oral hygiene, the most common risk factors for noma. METHODS: A vigorous literature searches were conducted on databases such as Scopus, Elsevier, Web of Science, PubMed, Virtual Health Library, and Google Scholar by inserting keywords such as 'noma' OR 'cancrum oris' OR 'cancrum oris cases'. A total of 65 articles gathered. Of these, 38 articles found to be eligible for this study. RESULTS: A total of 38 full-length articles were included in the review. According to the evidence gathered and summarized in this review, malnutrition, especially protein-energy malnutrition and vitamin deficiencies, makes the oral mucosa susceptible to opportunistic pathogens of noma, and then, in so doing, pathogens invade the oral cavities. Malnutrition has a bidirectional relationship with noma. Since noma is a disease of the oral cavity, poor oral hygiene has the potential of predispose and worsen the disease's progress. CONCLUSION: Malnutrition and poor oral hygiene found to be ingrained in the pathogenesis of noma. For effective management and prevention of noma, it is necessary to underpin adequate nutritional supplementation (including vitamins). As a primary prevention strategy, healthcare workers' training should be strengthened to improve the diagnosis and treatment of oral infections, including noma.