Abstract
OBJECTIVES: We aimed to fill the gaps of knowledge concerning incidence rates and temporal trend, clinical features and risk factors for death for Morganella morganii bloodstream infections (BSIs) in south Sweden. METHODS: This was an observational, population-based study including all patients with at least one blood culture positive for M. morganii between 2013 and 2023 in Skåne, south Sweden. RESULTS: A total of 211 episodes of M. morganii BSI in 201 patients were registered during the study period. A urinary tract-focused BSI was associated with a reduced risk of 90-day mortality (P = 0.0029), whereas a primary BSI was associated with 90-day mortality (P = 0.0112). A multivariate analysis including age, gender, Charlson comorbidity index (CCI), and immunosuppression revealed that higher CCI (odds ratio [OR] 1.25, 95% confidence interval [CI] 1.07-1.47, P = 0.0059) and immunosuppression (OR 3.26, 95% CI 1.45-7.47, P = 0.0045) was independently associated with all-cause mortality. CONCLUSIONS: M. morganii BSI is a disease among the elderly that most often acquired in individuals with comorbidities that are in close contact with health care. A urinary tract focus was associated with reduced risk of 90-day mortality, and higher CCI and immunosuppression were associated with 90-day all-cause mortality in a multivariate analysis.