Microwave-assisted synthesis of substituted hexahydro-pyrrolo[3,2-c]quinolines

微波辅助合成取代的六氢吡咯并[3,2-c]喹啉

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Abstract

New compounds with the ethyl hexahydro-1H-pyrrolo[3,2-c]quinoline-2-carboxylate skeleton were prepared by microwave-assisted intramolecular 1,3-dipolar cycloaddition reactions. The reactions were carried out under solvent-free conditions and compared with the same reaction in the presence of a solvent and a catalyst. Steric effects on the selectivity of the reaction were noted and evaluated.

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