The Drosophila FM7 - A Strain Contains a Fixed Translocation Involving the X and 4 Chromosomes

果蝇FM7——一种含有涉及X染色体和4号染色体的固定易位的品系

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Abstract

We discovered that a commonly used balancer chromosome - FM7-A, Tb (1) - exists as an uncharacterized translocation between the progenitor FM7a chromosome and a normal chromosome 4 . Genetic and cytological data evidence show that T ( 1 ; 4 ) FM7-A translocates about 5% of chromosome 1 material to an entire chromosome 4 , thus the large "chromosome 1 " segregant is lethal without the small "chromosome 4 " segregant, though the latter is viable and fertile without the former. We characterize this balancer chromosome to inform Drosophila molecular-geneticists of the structure as it may affect their use of this balancer chromosome and the interpretations of their results.

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