Abstract
Postimplantation syndrome (PIS) is a noninfectious systemic inflammatory response that often follows endovascular aneurysm repair, historically presumed to be a reaction to implanted graft materials. Although well-documented with stent graft use, PIS in the absence of stent grafts remains poorly understood. We present an instance of PIS after stentless thoracic endovascular aortic repair, which involves embolizing intimal tears with plugs and/or coils. This case highlights the need for further investigation into the pathophysiology of PIS. PIS can occur in the absence of a stent graft; prophylactic anti-inflammatory therapy may be warranted during endovascular interventions with large-volume aneurysms or false lumen thrombosis.