Abstract
INTRODUCTION: Hyperhidrosis is a chronic dermatologic condition that significantly impacts quality of life. While research has expanded in recent years, bibliometric analyses exploring publication trends remain limited. This study examined the 100 most-cited articles from 2015 to 2025 to assess research priorities. METHODS: A Scopus search was conducted on January 2, 2025, using the terms "hyperhidrosis", "primary hyperhidrosis", "secondary hyperhidrosis", and "excessive sweating". Non-English, abstract-only, and non-hyperhidrosis focused articles were excluded. Two reviewers screened and identified the 100 most-cited publications. Data were analyzed for publication year, authorship, country, study design, journal, and topic focus. The Oxford Centre for Evidence-Based Medicine Level of Evidence (LoE) framework was used to assess study quality. RESULTS: The majority (76%) of highly cited articles were published between 2015 and 2019. Randomized controlled trials (20%), cohort studies (18%), and case-control studies (16%) were the most common study types. Using LoE assessment, 33% of studies were level 1 (high-quality evidence). Research on treatments (55%) dominated, followed by quality of life (12%) and outcome measures (11%). The USA led in publication output. CONCLUSION: This bibliometric analysis identifies evolving research priorities toward minimally invasive treatments and patient-centered outcomes, providing direction for future research and improvements in clinical practice.