Dimethyl fumarate treatment alters NK cell function in multiple sclerosis
富马酸二甲酯治疗可改变多发性硬化症中的 NK 细胞功能
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作者：Matthew D Smith, Peter A Calabresi, Pavan Bhargava
Abstract
Dimethyl fumarate (DMF) treatment in multiple sclerosis (MS) increased the proportion of immunoregulatory CD56bright NK cells and this change was proportional to reductions in CD8+ memory T cells. DMF and monomethyl fumarate (MMF) treatment in vitro had directs effects on NK cells and promoted degranulation and cytotoxicity.
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