Fetal Health Classification from Cardiotocograph for Both Stages of Labor-A Soft-Computing-Based Approach

基于软计算方法的胎心监护图胎儿健康分级(适用于分娩两个阶段)

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Abstract

To date, cardiotocography (CTG) is the only non-invasive and cost-effective tool available for continuous monitoring of the fetal health. In spite of a marked growth in the automation of the CTG analysis, it still remains a challenging signal processing task. Complex and dynamic patterns of fetal heart are poorly interpreted. Particularly, the precise interpretation of the suspected cases is fairly low by both visual and automated methods. Also, the first and second stage of labor produce very different fetal heart rate (FHR) dynamics. Thus, a robust classification model takes both stages into consideration separately. In this work, the authors propose a machine-learning-based model, which was applied separately to both the stages of labor, using standard classifiers such as SVM, random forest (RF), multi-layer perceptron (MLP), and bagging to classify the CTG. The outcome was validated using the model performance measure, combined performance measure, and the ROC-AUC. Though AUC-ROC was sufficiently high for all the classifiers, the other parameters established a better performance by SVM and RF. For suspicious cases the accuracies of SVM and RF were 97.4% and 98%, respectively, whereas sensitivity was 96.4% and specificity was 98% approximately. In the second stage of labor the accuracies were 90.6% and 89.3% for SVM and RF, respectively. Limits of agreement for 95% between the manual annotation and the outcome of SVM and RF were (-0.05 to 0.01) and (-0.03 to 0.02). Henceforth, the proposed classification model is efficient and can be integrated into the automated decision support system.

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