The human parvovirus B19/human immunodeficiency virus co-infection in healthy eligible voluntary blood donors at the Blood Transfusion National Center in Kinshasa

金沙萨国家输血中心健康合格自愿献血者中人类细小病毒 B19/人类免疫缺陷病毒合并感染情况

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作者:Chabo Byaene Alain, Lufimbo Katawandja Antoine, Bizeti Nsangu Bizette, Pambu Dahlia, Tshibuela Beya Dophie, Muwonga Masidi Jérémie, Kayembe Nzongola-Nkasu Donatien, Ahuka Mundeke Steve

Conclusion

This research confirms our hypothesis: the seroprevalence of PVB19 in HIV-positive blood donors is equal to the seroprevalence of PVB19 in HIV-negative blood donors.

Methods

A random sample of 360 eligible blood donors were firstly examined for HIV antibodies by using ELISA automaton and so were categorized as HIV-positive donors and HIV-negative donors. Then the two categories of donors were examined for PVB19 IgG and IgM by using ELISA kits. The seroprevalence of PVB19 in HIV-positive donors was compared to that of HIV-negative donors by using chi-square test or Fisher's exact test. All statistical analyzes were performed with SPSS 21.

Results

The prevalences of PVB19 IgG and IgM in HIV-positive blood donors were 92.1% (35 of 38) and 44.7% (17 of 38), respectively and those in control group were 89.1% (287 of 322) and 46.3% (149 of 322), respectively. But for both IgG and IgM the difference was not statistically significant (p > 0.05).

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