Dynamic Contrast-Enhanced Magnetic Resonance Imaging Findings and the Relevance of Histopathological Findings in Intraocular Solitary Fibrous Tumors

动态增强磁共振成像结果及眼内孤立性纤维瘤组织病理学结果的相关性

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Abstract

Solitary fibrous tumors (SFT) are rare, and their intraocular occurrence is extremely uncommon. Therefore, magnetic resonance imaging (MRI) reports of intraocular SFT are limited, making preoperative diagnosis difficult. We present a case of primary choroidal SFT and explore dynamic contrast-enhanced (DCE) MRI findings along with histopathological findings. This investigation is expected to improve our understanding of the MRI findings of intraocular SFT. An 83-year-old woman presented with decreased vision in her right eye for several months. Computed tomography (CT) and MRI revealed a choroidal tumor with extension into the medial rectus muscle with suspected aggressive growth. The patient underwent right eye enucleation and recovered well after surgery. Histopathologically, diffuse STAT6 expression led to the final diagnosis of SFT. MRI findings typically expected for SFT were observed. T2-weighted images revealed heterogeneous signals with hyperintense and hypointense areas. DCE MRI revealed two patterns of time-intensity curves (TICs): marked enhancement and washout in T2-hyperintense areas and persistent enhancement in T2-hypointense areas. The intensity of T2-weighted imaging, enhancement pattern, and type of TICs in this case may be specific to intraocular SFT. An integrated evaluation of these findings may help differentiate SFT from other intraocular tumors.

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