Abstract
Here, we report the draft genome sequence of Stenotrophomonas maltophilia TUM26315, which exhibits resistance to cefiderocol and to aztreonam combined with ceftazidime-avibactam, despite no prior exposure. The isolate belonged to genomic group 6 and carried bla(L1B) and bla(L2B) β-lactamase genes. It also had a frameshift mutation in the cirA gene.