Fatal SV40-associated pneumonia and nephropathy following renal allotransplantation in rhesus macaque

恒河猴肾移植后发生致命的 SV40 相关肺炎和肾病

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作者:M Song, M S Mulvihill, K D Williams, B H Collins, A D Kirk

Abstract

Recrudescence of latent and dormant viruses may lead to overwhelming viremia in immunosuppressed hosts. In immunocompromised hosts, Simian virus 40 (SV40) reactivation is known to cause nephritis and demyelinating central nervous system disease. Here, we report SV40 viremia leading to fatal interstitial pneumonia in an immunosuppressed host following renal allotransplantation.

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