Microfluidic Devices: Integrated Microfluidic Device for Drug Studies of Early C. Elegans Embryogenesis (Adv. Sci. 5/2018)

微流控装置:用于秀丽隐杆线虫早期胚胎发生药物研究的集成微流控装置(Adv. Sci. 5/2018)

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Abstract

The feasibility of time‐controlled and reversible drug delivery to Caenorhabditis elegans (C. elegans) embryos immobilized on‐chip is demonstrated by regulated blocking of cytokinesis using Cytochalasin‐D. In article https://doi.org/10.1002/advs.201700751 by Martin A. M. Gijs and co‐workers, the implementation of versatile microfluidic protocols, including time‐controlled and reversible drug delivery to on‐chip, immobilized embryos, demonstrates the potential of the reported device for biochemical and pharmacological assays. [Image: see text]

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