Abstract
The efficiency of vermipreparations has been investigated with the help of the test-reactions on various invertebrate organisms, plants and microorganisms. The principal possibility of the use of biotest on the basis of yeast, fungi, algae, water and ground-based plants, sponges, protozoan, small crustaceans, oligochaetes for an estimation of biological activity of vermipreparations and in further and for definition of quality, selection of dose of medicinal complex preparations is shown.