Emerging role of exosomal-microRNA in obesity

外泌体microRNA在肥胖症中的新兴作用

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Abstract

Exosomes are small extracellular vesicles released by every cell in the human body and can be found in the circulation of almost every biological fluid. They majorly serve as a communication channel between cells. Exosomal microRNAs (miRNAs) are gaining wide attention in several pathophysiological conditions and are considered as early diagnostic and therapeutic targets. Recently, exosomal miRNAs have been identified as key players during obesity and coexisting risk elements, unraveling their pivotal role in the progression of obesity induced pathophysiological conditions. In this review, the latest developments in the role of exosomal cargo, specifically miRNAs, in obesity are highlighted. Additionally, we discuss their potential significance as early biomarkers and potential therapeutic targets for diagnosing and managing obesity and related diseases.

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