Difunctional oxidatively cleavable alkenyl boronates: application to cellular peroxide sensing from a fluorophore-quencher pair

双功能氧化裂解烯基硼酸酯:应用于荧光团-猝灭剂对的细胞过氧化物检测

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Abstract

This manuscript describes the development of difunctional alkenyl boronates that contain an oxidatively releasable cargo and an amine for attaching to groups that can improve physical properties or enhance cellular targeting. The design is applied to a FRET-based system that delivers a selective fluorescence response in oxidatively stressed cells.

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