A nonstop thrill ride from genes to the assembly of the T3SS injectisome

从基因到T3SS注射体的组装,全程惊险刺激。

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Abstract

The type three secretion system (T3SS) is a membrane-anchored nano-machine utilized by many pathogenic bacteria to inject effector proteins and thus take control of host cells. In a recent article, Kaval et al. reveal a striking colocalization of a T3SS-encoding locus, its transcriptional activators, protein products, and the complete structure at the cell membrane, which they claim provides evidence for a mechanism known as ‘transertion’.

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