Genomic analysis and assessment of pathogenic (toxicogenic) potential of Staphylococcus haemolyticus and Bacillus paranthracis consortia isolated from bovine mastitis in Russia

俄罗斯牛乳腺炎分离株溶血葡萄球菌和副炭疽芽孢杆菌的基因组分析及致病(毒性)潜力评估

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作者:Sergei Sokolov, Fedor Brovko, Alexander Solonin, Daria Nikanova, Ksenia Fursova, Olga Artyemieva, Evgenia Kolodina, Anatoly Sorokin, Margarita Shchannikova, Timur Dzhelyadin, Artem Ermakov, Khanafy Boziev, Natalia Zinovieva

Abstract

Three stable microbial consortia, each composed of Bacillus paranthracis and Staphylococcus haemolyticus strains, were isolated from milk of cows diagnosed with mastitis in three geographically remote regions of Russia. The composition of these consortia remained stable following multiple passages on culture media. Apparently, this stability is due to the structure of the microbial biofilms formed by the communities. The virulence of the consortia depended on the B. paranthracis strains. It seems plausible that the ability of the consortia to cause mastitis in cattle was affected by mutations of the cytK gene of B. paranthracis.

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