Abstract
Patient's psychological and aesthetic quality is affected by the appearance of scars since atrophic scars might be caused by infections or inflammations that resulted from preoperative procedures. Non-surgical methods have recently been developed to increase patient satisfaction and improve the appearance of scars. In our understanding, there has not been much published medical research assessing how well nanofat grafting techniques work in terms of treating facial scars. With a six-month follow-up after the intervention, this research intends to provide four cases where scars in the facial area were controlled utilizing these materials. Based on the cases shown, it can be seen that following the procedure, the scar's measurements were minimized, its color and texture improved, and there was no pain or itching. Given its safety and effectiveness, autologous nanofat grafting has become one of the most important and well-liked aesthetic procedures. It has been discussed how modifying injectable nanofat using fine needles has opened up new clinical applications for rejuvenating aesthetic medicine. Additionally, it was pointed out that injectable PRF has gained attention due to its high concentration of growth factors, which help to promote healing and improve the appearance of the skin. Furthermore, it can be efficiently shared with autogenous nanofat grafts, which support and enhance the efficacy of adipose-derived stem cells (ADSCs) and improve adipocyte blood circulation. The current use of modified nanofat in the treatment of facial scars is supported by the procedure's safety and low risk of injection-site problems. The consistent efficacy of modified-nanofat injection in the management of depression-related facial scars was validated by the outcomes of patient satisfaction surveys and physician evaluations.