Abstract
Structurally diverse alcohols (or aldehydes) react with (triisopropylsilyl)acetylene to form α,β-acetylenic ketones (ynones) in good to excellent yield. This method for oxidative alkynylation exploits the commercially available air-stable precatalyst RuHCl(CO)(PPh(3))(3) rather than the iodide-bound precatalyst RuI(η(3)-C(3)H(5))(CO)(3), which is sensitive and not available for purchase.