Harnessing the β-Silicon Effect for Regioselective and Stereoselective Rhodium(II)-Catalyzed C-H Functionalization by Donor/Acceptor Carbenes Derived from 1-Sulfonyl-1,2,3-triazoles

The regioselective and enantioselective intermolecular sp(3) C-H functionalization of silicon-substituted alkanes was accomplished using Rh(2)( S-NTTL)(4) with readily available 1-sulfonyl-1,2,3-triazoles as carbene precursors. These reactions generate a diverse array of stereodefined substituted silaalkanes.