Ruthenium-catalyzed γ-carbolinium ion formation from aryl azides; synthesis of dimebolin

钌催化芳基叠氮化物生成γ-咔啉正离子;二甲溴林的合成

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Abstract

A range of γ-carbolines were produced stereoselectively from ruthenium(III)-catalyzed reactions of 3-pyridyl substituted aryl azides. Other catalysts and conditions were neither as selective nor as high-yielding. This method was used to synthesize dimebolin in a concise and efficient manner.

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