Rare Neuromelioidosis Case that Required Long Intensive Phase Therapy

Melioidosis, an infectious disease caused by Burkholderia pseudomallei, is endemic in tropical regions, including the Indian subcontinent. It can affect several systems in the body and has high mortality and morbidity. Neuromelioidosis is a rare central nervous system manifestation of melioidosis. We report a case of a 37-year-old man who had disseminated melioidosis with severe central nervous system involvement, with radiological demonstration of spread along white matter tracts. Our report emphasizes the importance of prolonged intensive phase therapy in achieving clinical remission and preventing relapse.