Impact of deoxynivalenol on the intestinal microflora of pigs

呕吐毒素对猪肠道菌群的影响

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作者:Yann J Waché, Charlotte Valat, Gilbert Postollec, Stephanie Bougeard, Christine Burel, Isabelle P Oswald, Philippe Fravalo

Abstract

Deoxynivalenol (DON), a mycotoxin produced by some Fusarium species, is a frequent contaminant of cereal. In the present study, 24 weanling piglets received either control feed or feed naturally contaminated with DON (2.8 mg/kg) for four weeks. Consumption of contaminated feed significantly reduced the animal weight gain during the first week of the experiment, but had a moderate effect on cultivable bacteria in the pig intestine. By contrast, changes in the intestinal microflora were observed by Capillary Electrophoresis Single-Stranded Conformation Polymorphism (CE-SSCP) in DON-exposed animals, suggesting an impact of this toxin on the dynamics of intestinal bacteria communities.

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