Differential T-Cell Immunity to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in mRNA-1273- and BNT162b2-Vaccinated Individuals
mRNA-1273 和 BNT162b2 疫苗接种者对严重急性呼吸道综合征冠状病毒 2 (SARS-CoV-2) 的差异性 T 细胞免疫
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作者：Kathleen M E Gallagher, Mark B Leick, Rebecca C Larson, Trisha R Berger, Katelin Katsis, Jennifer Y Yam, Marcela V Maus
Abstract
COVID-19 breakthrough cases among vaccinated individuals demonstrate the value of measuring long-term immunity to SARS-CoV-2 and its variants. We demonstrate that anti-spike T-cell responses and IgG antibody levels are maintained but decrease over time and are lower in BNT162b2- versus mRNA-1273-vaccinated individuals. T-cell responses to the variants are relatively unaffected.
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