Whole genome sequencing analysis of a novel exopolysaccharide-producing Bacillus velezensis and its impact on the quality of soy sauce

对一种新型产胞外多糖的贝莱斯芽孢杆菌进行全基因组测序分析及其对酱油品质的影响

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Abstract

This study aimed to develop a novel exopolysaccharides (EPS)-producing strain, Bacillus velezensis KUST4317 (BVK), isolated from soy sauce as a multifunctional starter culture for fermented foods. The evaluation mainly focused on its biosafety, metabolic potential, and functional characteristics. Genomic analysis confirmed the strain's biosafety, identifying only seven non-critical antibiotic resistance genes and no virulence factors. BVK exhibited a high EPS yield (250 mg/L), which contributed to increased soy sauce viscosity (1-1.2 mPa·s) and exhibited strong antioxidant activity (76.4 % DPPH scavenging). Metabolomic profiling revealed that BVK uniquely produces flavor-enhancing compounds (e.g., benzyl alcohol, pyrazines), while preserving essential taste components. Further mechanistic analysis identified ATP-Binding Cassette (ABC) transporters as key pathway involved in EPS biosynthesis. These findings highlight the potential of BVK to enhance both the functional and sensory qualities of fermented foods.

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