Syn- and anti-rotamers of the ortho-stereoisomer [Pt{(o-BrC(6)F(4))N(CH(2))(2)NEt(2)}Cl(py)]

邻位立体异构体的顺式和反式旋转异构体 [Pt{(o-BrC(6)F(4))N(CH(2))(2)NEt(2)}Cl(py)]

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Abstract

The crystal structure of the ortho-isomer trans-[N-(2-bromo-3,4,5,6-tetrafluorophenyl)-N',N'-diethylethane-1,2-diaminato(1-)]chloridopyridineplatinum(II), [PtBr(0.1)(C(12)H(14)BrF(4)N(2))Cl(0.9)(C(5)H(5)N)][PtBr(0.4)(C(12)H(14)BrF(4)N(2))Cl(0.6)(C(5)H(5)N)] or [Pt{(o-BrC(6)F(4))N(CH(2))(2)NEt(2)}Cl(py)], 1o, revealed syn and anti rotamers in a 1:1 ratio in the solid state. 1o crystallizes in the centrosymmetric space group P1. The Pt-coordinated Cl ligand exhibits partial occupancy with Br, predominantly in the syn-rotamer. Notably, agostic interactions are observed between the Pt centre and a H atom of one of the ethyl groups. The ortho-isomer 1o was successfully isolated as a side product from the reaction of [Pt{H(2)N(CH(2))(2)NEt(2)}Cl(2)], Tl(2)CO(3) and C(6)F(5)Br. While the para-isomer [Pt{(p-BrC(6)F(4))N(CH(2))(2)NEt(2)}Cl(py)], 1p, is the main product, the higher solubility of 1o facilitates its isolation.

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