The Uranyl Cation as a Visible-Light Photocatalyst for C(sp(3) )-H Fluorination

铀酰阳离子作为可见光光催化剂用于C(sp(3) )-H氟化反应

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Abstract

The fluorination of unactivated C(sp(3) )-H bonds remains a desirable and challenging transformation for pharmaceutical, agricultural, and materials scientists. Previous methods for this transformation have used bench-stable fluorine atom sources; however, many still rely on the use of UV-active photocatalysts for the requisite high-energy hydrogen atom abstraction event. Uranyl nitrate hexahydrate is described as a convenient, hydrogen atom abstraction catalyst that can mediate fluorinations of certain alkanes upon activation with visible light.

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