Toxicity and chronic effects of deltamethrin exposure on zebrafish (Danio rerio) as a reference model for freshwater fish community

溴氰菊酯暴露对斑马鱼(Danio rerio)的毒性和慢性影响作为淡水鱼群落的参考模型

阅读:5
作者:Stefan-Adrian Strungaru, Gabriel Plavan, Alin Ciobica, Mircea Nicoara, Madalina Andreea Robea, Carmen Solcan, Adriana Petrovici

Abstract

In this study zebrafish specimens were exposed for 15 days to 0.25, 0.5, 1 and 2 μg L-1 non-lethal concentrations of deltamethrin (DM) knowing that is the active compound in insecticides used on agricultural crops. They were investigated important issues resulted during the chronic exposure with DM: effects on aggressive behavior and swimming performances knowing that is a high neurotoxic compound; toxicity on nervous system investigated on telencephalon, optic tectum and cerebellum; activity of PCNA, p53 and TUNEL as toxicity markers in immunocytochemistry of the histological samples; changes of elements concentrations in the fish body and their role in detoxification of DM. This scenario investigated the harmful effects of this compound for freshwater fish communities. The aggressive behavior significantly increased and remained constant for the concentration 0.5 μg L-1. They were not evidences in changing of anxiety level and swimming performances. The nervous system suffered significant damage for all studied concentrations and confirmed the changes in the behavior. Selenium concentration in the body decreased and may be involved in the detoxification processes.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。