Apoferritin modified magnetic particles as doxorubicin carriers for anticancer drug delivery

脱铁铁蛋白修饰磁性粒子作为阿霉素载体用于抗癌药物输送

阅读:6
作者:Iva Blazkova, Hoai Viet Nguyen, Simona Dostalova, Pavel Kopel, Maja Stanisavljevic, Marketa Vaculovicova, Marie Stiborova, Tomas Eckschlager, Rene Kizek, Vojtech Adam

Abstract

Magnetic particle mediated transport in combination with nanomaterial based drug carrier has a great potential for targeted cancer therapy. In this study, doxorubicin encapsulation into the apoferritin and its conjugation with magnetic particles was investigated by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF). The quantification of encapsulated doxorubicin was performed by fluorescence spectroscopy and compared to CE-LIF. Moreover, the significant enhancement of the doxorubicin signal was observed by addition of methanol into the sample solution.

特别声明

1、本页面内容包含部分的内容是基于公开信息的合理引用;引用内容仅为补充信息,不代表本站立场。

2、若认为本页面引用内容涉及侵权,请及时与本站联系,我们将第一时间处理。

3、其他媒体/个人如需使用本页面原创内容,需注明“来源:[生知库]”并获得授权;使用引用内容的,需自行联系原作者获得许可。

4、投稿及合作请联系:info@biocloudy.com。